Open Access
Translator Disclaimer
1 July 1999 EFFECTS OF MALATHION ON DISEASE SUSCEPTIBILITY IN WOODHOUSE'S TOADS
Sharon K. Taylor, Elizabeth S. Williams, Ken W. Mills
Author Affiliations +
Abstract

Adult male Woodhouse's toads (Bufo woodhousi) developed clinical disease, hepatomegaly, and died at a higher rate when externally exposed once to either a high or low sublethal dose (0.011 or 0.0011 mg malathion/g toad) of field grade malathion and challenged with a sublethal dose of Aeromonas hydrophila injected intraperintoneally (1.1 × 104 bacteria/g toad) when compared to toads not exposed to malathion but challenged with A. hydrophila (P < 0.007). Toads exposed to malathion (high or low dose) and challenged with A. hydrophila had clinical disease, hepatomegaly, and died at a higher rate [9 (90%) of 10] than toads exposed to malathion alone (P < 0.002). Toads exposed to the high and low doses of malathion had a 22% and 17% decrease in brain cholinesterase levels, respectively, when they were compared to nonmalathion exposed toads (P < 0.025, P < 0.006). It appears that field grade malathion applied externally to adult Woodhouse's toads may cause increased disease susceptibility when challenged with a potentially pathogenic bacteria.

Taylor, Williams, and Mills: EFFECTS OF MALATHION ON DISEASE SUSCEPTIBILITY IN WOODHOUSE'S TOADS
Sharon K. Taylor, Elizabeth S. Williams, and Ken W. Mills "EFFECTS OF MALATHION ON DISEASE SUSCEPTIBILITY IN WOODHOUSE'S TOADS," Journal of Wildlife Diseases 35(3), 536-541, (1 July 1999). https://doi.org/10.7589/0090-3558-35.3.536
Received: 6 August 1998; Published: 1 July 1999
JOURNAL ARTICLE
6 PAGES


Share
SHARE
KEYWORDS
Aeromonas hydrophila
amphibian
Bufo woodhousi
malathion
organophosphorus pesticide
pesticide
Woodhouse's toad
RIGHTS & PERMISSIONS
Get copyright permission
Back to Top