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1 October 2005 Malignant Lymphoma in a West Indian Manatee (Trichechus manatus)
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We identified a malignant lymphoma infiltrating the lung, liver, kidney, mesenteric lymph nodes, and eye as the cause of death in a male West Indian manatee (Trichechus manatus). Diagnosis was based on gross, histopathologic, and immunohistochemical studies. Tissue samples from ten organs were included in a tissue microarray and sections from this array were subjected to immunohistochemical staining. The cytoplasm of the neoplastic lymphocytes identified in six organs was positive for CD3, a marker for T-cell differentiation. The neoplastic cells were negative for CD79a, a marker for B-cell differentiation. The cause of this neoplasm was not determined. This is the first report of malignant lymphoma in the mammal order Sirenia.

Hammer, Klausen, Knold, Dietz, and Dutoit: Malignant Lymphoma in a West Indian Manatee (Trichechus manatus)
Anne S. Hammer, Bjarne Klausen, Steffen Knold, Hans H. Dietz, and Stephen J. Hamilton Dutoit "Malignant Lymphoma in a West Indian Manatee (Trichechus manatus)," Journal of Wildlife Diseases 41(4), 834-838, (1 October 2005).
Received: 3 June 2004; Published: 1 October 2005

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