An improved understanding of the spatial structure and movements of harvested populations can promote more efficient management of marine resources. Conventional tagging is a valuable approach to study the movements of marine fishes due to its relatively low expense and the typically broad spatial extent over which movements can be characterized. We present the findings of multiple tag return studies initiated in the estuaries of North Carolina during the past two decades to better understand habitat residency and migration patterns of Southern Flounder Paralichthys lethostigma, an economically important marine flatfish in the southeastern USA. Tag return data indicated large-scale (>50 km) movements of relatively large fish in the fall, which were presumably associated with offshore winter spawning migrations. Nearly all Southern Flounder that demonstrated large-scale movement were recovered to the south of the system in which they were tagged, suggesting that the spawning activity of fish using North Carolina estuaries may be concentrated mostly off the southeastern U.S. continental shelf. Tag returns from within multiple estuarine systems during the spring and summer were in close proximity to release sites (typically < 1 km), suggesting limited movement during estuarine residency. Recaptures in the spring of fish tagged the previous summer or fall were also in close proximity to release sites, in some cases within the same estuarine creek, indicating limited movement of fish overwintering in the estuary as well. Our findings reveal saltatory movement dynamics of Southern Flounder characterized by limited movement during estuarine residency and large-scale movements in the fall associated with spawning migrations. Our synthesis of several tag return studies across multiple spatial scales should contribute to a better alignment of Southern Flounder management with their spatial dynamics.