Light at Night and Cancer Risk¶

Eva Schernhammer; Karl Schulmeister

doi:10.1562/SA-03-28.1

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Eva Schernhammer,^1,* Karl Schulmeister²

¹aChanning Laboratory, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School,
²bARC Seibersdorf Research, Health Physics Division, Seibersdorf, Austria

^**To whom correspondence should be addressed: Department of Medicine, Brigham and Womens Hospital, Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA. Fax: 617-525-2008; eva.schernhammer@channing.harvard.edu

Abstract

Environmental lighting powerfully suppresses the physiologic release of melatonin, which typically peaks in the middle of the night. This decreased melatonin production has been hypothesized to increase the risk of cancer. Evidence from experimental studies supports a link between melatonin and tumor growth. There is also fairly consistent indirect evidence from observational studies for an association between melatonin suppression, using night work as a surrogate, and breast cancer risk.

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Eva Schernhammer and Karl Schulmeister "Light at Night and Cancer Risk," Photochemistry and Photobiology 79(4), 316-318, (1 April 2004). https://doi.org/10.1562/SA-03-28.1

Received: 9 October 2003; Accepted: 1 February 2004; Published: 1 April 2004

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