Two new species of Tibouchina from Central Brazil are described and illustrated and compared with their relatives. Tibouchina albescens is similar to T. verticillaris in its shrubby habit and leaf indumentum, but differs in having opposite leaves and peeling stem bark, and lacking trichomes. Tibouchina nigricans is similar to T. aegopogon in its habit, i.e. having only a single stem. Tibouchina nigricans differs from this species in its appressed-strigose, dendritic trichomes on the leaf abaxial surface. Comments on the taxonomy, geographical distribution, habitat and conservation status are provided, as well as a key to the species of Tibouchina s. s. from Goiás State.