Integrating cover crops (CCs) in dryland crop rotations could help in controlling herbicide-resistant weeds. Field experiments were conducted at Kansas State University Agricultural Research Center near Hays, KS, from 2020 to 2023 to determine the effect of fall-planted CCs on weed suppression in grain sorghum [Sorghum bicolor (L.) Moench], crop yield, and net returns in no-till dryland winter wheat (Triticum aestivum L.)–grain sorghum–fallow (W-S-F) rotation. The field site had a natural seedbank of glyphosate-resistant (GR) kochia [Bassia scoparia (L.) A. J. Scott] and Palmer amaranth (Amaranthus palmeri S. Watson). A CC mixture [winter triticale (×Triticosecale Wittm. ex A. Camus [Secale × Triticum])–winter peas (Pisum sativum L.)–canola (Brassica napus L.)–radish (Raphanus sativus L.)] was planted after wheat harvest and terminated at triticale heading stage before sorghum planting. Treatments included nontreated control, chemical fallow, CC terminated with glyphosate (GLY), and CC terminated with GLY+ acetochlor/atrazine (ACR/ATZ). Across 3 yr, CC terminated with GLY+ACR/ATZ reduced total weed density by 34% to 81% and total weed biomass by 45% to 73% compared with chemical fallow during the sorghum growing season. Average grain sorghum yield was 786 to 1,432 kg ha–¹ and did not differ between chemical fallow and CC terminated with GLY+ ACR/ATZ. However, net returns were lower with both CC treatments (–US$275 to US$66) in all 3 yr compared with chemical fallow (–US$111 to US$120). These results suggest that fallow replacement with fall-planted CCs in the W-S-F rotation can help suppress GR B. scoparia and A. palmeri in the subsequent grain sorghum. However, the cost of integrating CCs exceeded the benefits of improved weed control, and lower net returns were recorded in all 3 yr compared with chemical fallow.