The succulent endemic species of Crassulaceae in Argentina are reviewed and three new taxa are described. Echeveria argentinensis is a new species already collected 80 years ago in the Quebrada of Humahuaca at Jujuy between 2700 and 3600 m, determined primarily as E. peruviana. Hutchison recognized it as a new species 50 years ago and recorded this epithet in the herbarium sheets, but he never described it. Both species are close and belong to series Racemosae, they share having tuberous roots, but the new species has smaller rosettes and leaves than E. peruviana, a longer stem but smaller scapes and less flowers with erect or adpressed sepals and an opposite petal color pattern, red proximally and yellow distally. Populations from Salta are described as E. argentinensis var. kieslingii. They are smaller, lighter or glaucous in color, leaves are obovate and cuspidate when young, scapes are shorter with less but slightly larger flowers that have a constriction near the middle and are mostly yellow in color. They are distributed along the Quebrada del Toro between 2050 to 2350, in more exposed situations. Also from Salta, but further South, near the border with Tucumán, E. saltensis is described. It resembles E. chiclensis var. cantaensis from Perú, with narrow oblong to linear leaves, in this case with a very interesting multicolored raster on its surface, less tuberous roots, shorter sepals and longer but wider petals, more yellowish than the Peruvian species. This is perhaps the southernmost and lowest growing Echeveria in South America. An extended description of Sedum jujuyense, the only endemic Sedum of Argentina together with some photographs of it are also given.