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22 July 2020 Effects of dietary red-osier dogwood (Cornus stolonifera) on growth performance, blood profile, ileal morphology, and oxidative status in weaned pigs challenged with Escherichia coli K88+
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Abstract

A total of 28 piglets weaned at 21 d of age (6.94 ± 0.28 kg of body weight) were assigned to one of four dietary treatments for 14 d: (1) negative control (NC; a corn–wheat–soybean meal diet), (2) positive control [PC; NC + 0.025% antimicrobial growth promoter (AGP)], (3) ROD2 [2% red-osier dogwood (ROD)], and (4) ROD4 (4% ROD). All pigs were orally inoculated with Escherichia coli K88+ on day 8. The pre-planned orthogonal test was performed to compare (1) NC vs. PC and (2) NC vs. ROD. The inclusion of ROD in a nursery diet increased (P < 0.05) superoxide dismutase (SOD) activities and decreased (P < 0.05) malondialdehyde (MDA) concentrations in the serum. Moreover, pigs fed with ROD diets had shallower (P < 0.05) crypt depth and higher (P < 0.05) villus height to crypt depth ratio than those fed the NC diet. Dietary AGP supplementation reduced (P < 0.05) the MDA concentration in the ileum and serum at 24 h after challenge, and improved (P < 0.01) the SOD activities in the serum. In conclusion, the inclusion of ROD in a nursery diet enhanced the antioxidative defense system and intestinal morphology, showing comparable effects with AGP supplementation.

Copyright remains with authors B. Koo, S.B. Amarakoon, B. Jayaraman, Y. Shang, O. Karmin, and C.M. Nyachoti or their institutions, and © Her Majesty the Queen in right of Canada 2020. Permission for reuse (free in most cases) can be obtained from copyright.com.
Bonjin Koo, Sirini Budhika Amarakoon, Balachandar Jayaraman, Yaw L. Siow, Suvira Prashar, Yue Shang, O. Karmin, and Charles Martin Nyachoti "Effects of dietary red-osier dogwood (Cornus stolonifera) on growth performance, blood profile, ileal morphology, and oxidative status in weaned pigs challenged with Escherichia coli K88+," Canadian Journal of Animal Science 101(1), 96-105, (22 July 2020). https://doi.org/10.1139/cjas-2019-0188
Received: 22 October 2019; Accepted: 14 April 2020; Published: 22 July 2020
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