The taxonomy of Hypotrachyna subg. Everniastrum (Hale ex Sipman) Divakar, A.Crespo, Sipman, Elix & Lumbsch from China is revised based on morphological, chemical and phylogenetic analyses. Four species new to science (Hypotrachyna corallifera Xin Y.Wang & Li S.Wang, sp. nov., H. longicilia Xin Y.Wang & Li S.Wang, sp. nov., H. puerensis Xin Y.Wang & Li S.Wang, sp. nov., and H. yunnana Xin Y.Wang & Li S.Wang, sp. nov.) and a new floristic record for one species (H. catawbiensis (Degel.) Divakar, A.Crespo, Sipman, Elix & Lumbsch) in China are reported, and a total of fifteen species are confirmed, including all the species previously reported from China. Specimens of three species (H. cirrhata (Fr.) Divakar, A.Crespo, Sipman, Elix & Lumbsch, H. nepalensis (Taylor) Divakar, A.Crespo, Sipman, Elix & Lumbsch and H. vexans (Zahlbr. ex W.L.Culb. & C.F.Culb.) Divakar, A.Crespo, Sipman, Elix & Lumbsch) from the type localities are sequenced, providing fundamental molecular data for species delimitation. New chemical varieties are detected for H. diffractaica (Y.M.Jiang & J.C.Wei) Divakar, A.Crespo, Sipman, Elix & Lumbsch. Detailed descriptions and figures for the new species and a key to all known species from China are provided.