BioOne.org will be down briefly for maintenance on 17 December 2024 between 18:00-22:00 Pacific Time US. We apologize for any inconvenience.
How to translate text using browser tools
1 March 2003 BREAKDOWN IN CORRELATIONS DURING LABORATORY EVOLUTION. I. COMPARATIVE ANALYSES OF DROSOPHILA POPULATIONS
John P. Phelan, Margaret A. Archer, Kelly A. Beckman, Adam K. Chippindale, Theodore J. Nusbaum, Michael R. Rose
Author Affiliations +
Abstract

We provide evidence from comparisons of populations of Drosophila that evolutionary correlations between longevity and stress resistance break down over the course of laboratory evolution. Using 15 distinct evolutionary regimes, we created 75 populations that were differentiated for early fecundity, longevity, starvation resistance, desiccation resistance, and developmental time. In earlier experiments, selection for postponed aging produced increases in stress resistance, whereas selection for increased stress resistance produced increases in longevity. Direct estimates of correlations also indicated an antagonistic relationship between early fecundity on one hand and longevity or stress resistance on the other. Laboratory evolution of extreme values of stress resistance, however, led to a breakdown in these evolutionary relationships. There was no evidence that these significant changes in correlation resulted from genotype-by-environment interactions or inbreeding. These findings suggest that correlations between functional characters are not necessarily durable features of a species, and that short-term evolutionary responses cannot be extrapolated reliably to longer-term evolutionary patterns.

John P. Phelan, Margaret A. Archer, Kelly A. Beckman, Adam K. Chippindale, Theodore J. Nusbaum, and Michael R. Rose "BREAKDOWN IN CORRELATIONS DURING LABORATORY EVOLUTION. I. COMPARATIVE ANALYSES OF DROSOPHILA POPULATIONS," Evolution 57(3), 527-535, (1 March 2003). https://doi.org/10.1554/0014-3820(2003)057[0527:BICDLE]2.0.CO;2
Received: 28 January 2002; Accepted: 18 November 2002; Published: 1 March 2003
JOURNAL ARTICLE
9 PAGES

This article is only available to subscribers.
It is not available for individual sale.
+ SAVE TO MY LIBRARY

KEYWORDS
antagonistic pleiotropy
correlations
fitness characters
Laboratory evolution
longevity
stress resistance selection
RIGHTS & PERMISSIONS
Get copyright permission
Back to Top