Forest fragmentation due to forestry management, agricultural activities, or urban development decreases habitat availability for some animals. This decline in forest area has been implicated in songbird population declines via changes in nest predation pressures. The increase of edge habitat that accompanies deforestation also may affect songbird breeding activities through changes in predation risk. This study found evidence for an interaction effect of distance from edge (1, 15, 30, and 45 m) and adjacent landscape matrix (residential or forested) on nest predation rates using an artificial nest design. In fragments bordered by other forested patches, nest predation rates were lowest 1 m from the edge and higher 15–45 m into the forest patch. When the forest fragment was embedded in a landscape matrix of residential and developed plots, predation rate was highest closest to the edge of the fragment.